Pneumocystis jirovecii in pleural infection: a nucleic acid amplification study

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Pneumocystis jirovecii in pleural infection: a nucleic acid amplification study.

Pleural infection is associated with 20% mortality in the 80 000 new cases per year in the UK and USA. Streptococcus species cause w50% of community-acquired bacterial pleural infection. Staphylococcus aureus and anaerobes are isolated in 8% and 20% of cases, respectively, and 12% of pleural infections yield polymicrobial cultures. However, even using culture and nucleic acid amplification tech...

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The possible presence of Pneumocystis among healthy adults was examined by detecting Pneumocystis jirovecii-specific DNA in prospectively obtained oropharyngeal wash samples from 50 persons without underlying lung disease or immunosuppression. Pneumocystis carriage, defined by detecting Pneumocystis DNA by nested polymerase chain reaction in 2 independent analyses plus successful mitochondrial ...

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Spelling Pneumocystis jirovecii

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ژورنال

عنوان ژورنال: Thorax

سال: 2010

ISSN: 0040-6376

DOI: 10.1136/thx.2009.129940